Ciprofloxacin Induced Antibiomania

Ciprofloxacin-induced crystal nephropathy.

Ciprofloxacin is a commonly used antibiotic. Renal side effects are rare and are usually immune mediated. Clinical and experimental studies have suggested that crystalluria and crystal nephropathy occur in alkaline urine. Preexisting kidney function impairment, high dose of the medication, and advanced age predispose to this complication. We report a case of crystal nephropathy in a young woman...

Ciprofloxacin Induced Chondrotoxicity and Tendinopathy

Ciprofloxacin is one of the fluoroquinolones with a wide clinical acceptability. Rescently there are increasing reports on Ciprofloxacin induce Chondrotoxicity and Tendinopathy in Animal experiment and clinical experience which is of great clinical concern. A comprehensive survey and review of literaure on reported ciprofloxacin induced Chondrotoxicity and Tendinopathy in Humans and Animals was...

Ciprofloxacin-induced allergic interstitial nephritis.

Negative Myoclonus Induced by Ciprofloxacin

BACKGROUND Negative myoclonus is characterized by a brief sudden loss of muscle activity, and can be caused by a variety of acquired factors and epilepsy syndromes. PHENOMENOLOGY SHOWN We show a clear video example of a patient with an extensive negative myoclonus that was induced by ciprofloxacin. EDUCATIONAL VALUE Several neurotoxic effects have been associated with the use of ciprofloxac...

Vorinostat Pretreatment Enhanced Ciprofloxacin-Induced Antibacterial Activity

The mechanism of ciprofloxacin action involves interference with transcription and replication of bacterial DNA, which results in elevated oxidative stress, and bacterial cell death. Vorinostat was shown to induce oxidative DNA damage. In the current work, the possibility for interactive effect of vorinotat on ciprofloxacin-induced cytotoxicity against a number of reference bacteria was investi...